Amerizole: Metronidazole- Antiprotozoal — Bactericidal

Composition

  • Each 5 ml suspension contains:200 mg Benzoyl Metronidazole (equivalent to 125 mg metronidazole).
  • Each tablet contains: 250 mg Metronidazole.

Properties

The active principle of Amrizole is metronidazole which has strong antiprotozoal and bactericidal actions (against anaerobic infections involving septicaemia, necrotising pneumonia, puerperal sepsis, pelvic abscesses, cellulitis and postoperative wound infections).

It is effective against Trichomonas vaginalis and protozoa including Entamoeba histolytica and Giardia lamblia.

amerizol susp by pharmacia1
amerizol susp by pharmacia1

Indications

  1. Amerizole is used in the treatment of trichomoniasis of the genito-urinary tract in males and females.
  2. In amoebiasis, Amrizole is effective at all sites of infection and is used in the treatment of dysentery and amoebic abscesses as well as for the eradication of E histolytica from patients passing cysts.
  3. For prevention and treatment of anaerobic infections in patients undergoing abdorninal and gynaecological surgery.
  4. For treatment of giardiasis and Vincent’s infection.
أمريزول اقراص
أمريزول اقراص

Dosage

Treatment of acute amoebic dysentery, chronic intestinal amoebiasis, hepatic and other extra-intestinal amoebiasis

  • Adults: 1 to 2 tablets three times daily for 5 to 10 days.
  • Children (5 — 12 years): ½ to 1 tablet three times daily 5 to 10 days.
  • Adults: 2 to 4 teaspoonfuls three times daily for 5 to 10 days.
  • Children ( up to 3 years ): ½ to 1 teaspoonful three times daily for 5 to 10 days.
  • Children (3 to 7 years): ¾ to 1 1⁄2 teaspoonful three times daily for 5 to 10 days.
  • Children (7 to 10 years): 1 to 2 teaspoonfuls three times daily for 5 to 10 days.

Treatment of trichomoniasis

  • One tablet three times daily for 7 days. A second course of treatment may be given, if needed , after an interval of 4 to 6 weeks. The concomitant treatment of sexual consorts is recommended.
  • Adults and children over 10 years: 2 teaspoonfuls three times daily for 7 days. A second course of treatment may be given, if needed, after an interval of 4 to 6 weeks. The concomitant treatment of sexual cmsorts is recommended.
  • Children ( up to 3 years ): 1 ¼ teaspoonful daily for 7 days.
  • Children (3 to 7 years): 1 1⁄2 teaspoonfuls daily for 7 days.
  • Children (7 to 10 years): 2 ½ teaspoonfuls daily for 7 days.
أمريزول شراب - النشرة الداخلية
أمريزول شراب – النشرة الداخلية

Treatment of giardiasis (lambliasis)

  • One tablet three times daily for 10 days.
  • Adults: 2 to 4 teaspoonfuls three times daily for 10 days.
  • Children: proportional, as for amoebiasis.

For prevention and treatment of anaerobic infections

  • 1 to 2 tablets three times daily for 7 days.
  • 2 to 4 teaspoonfuls three times daily for 7 days.
Amerizol suspension- new
Amerizol suspension- new

Side effects

Amrizole is usually well tolerated. But flatulence and mild gastric upset may occur in hypersensitive individuals.

Contra — indications

Metronidazole should not be used in patients with blood dyscrasias or with active disease of the central nervous system. It is advisable to avoid its use during pregnancy.

Drug Interactions

Some patients may develop abdominal distress, vorniting, flushing or headache if they drink alcoholic beverages during a course of treatment.

أمريزول Amerizole
أمريزول Amerizole

Produced by: AMRIYA PHARM. IND. – ALEXANDRIA/ EGYPT.

Patient information leaflet

ENG - Patient Information Leaflet
AMERIZOLE – Patient Information Leaflet
Patient_Information_Leaflet
أمريزول- النشرة الداخلية

Categories: Agents that reduce seizure threshold; Alimentary Tract and Metabolism; Anti-Bacterial Agents; Anti-Infective Agents; Antibacterials for Systemic Use; Antiinfectives and Antiseptics for Local Oral Treatment; Antiinfectives for Systemic Use; Antiparasitic Agents; Antiprotozoals; Cytochrome P-450 CYP2A6 Substrates; Cytochrome P-450; Drugs for Acid Related Disorders; Drugs for Peptic Ulcer and Gastro-Oesophageal Reflux Disease (Gord); Gynecological Anti Infectives and Antiseptics; Imidazole Derivatives; Imidazoles Miscellaneous Antiprotozoals; Miscellaneous Local Anti-infectives; Nitro Compounds; Nitroimidazole Antimicrobial

Tags: Imidazole derivatives; metronidazole; J01XD01.

Amrizole- Arabic information

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Amrizole- Arabic Information

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