Metrozole: Metronidazole Suspension

COMPOSITION

Antiprotozoal & antibacterial Oral Suspension contains 200 mg benzoyl metronidazole (Equivalent to 125 mg metronidazole per 5 ml).

PROPERTIES

Metrozole suspension contains benzoyl metronidazole, the prototype broad spectrum antiprotozoal agent. Metrozole suspension exerts a potent efficacy in eradication Of protozoal infections caused by Entamoeba histolytica, Giardia lamblia and Trichomonas vaginalis. It also possesses very strong bactericidal action against anaerobic infections. Metrozole spectrum of activity extends to include anaerobic Gram-negative bacilli (Bacteroides and Fusobacterium species), Gram-positive bacilli (Clostridium species and some strains of Eubacterium) and all anaerobic cocci.

Metrozole suspension has a pleasant and palatable taste specially formulated for children.

Metrozole susp.
Metrozole susp.

INDICATIONS

  • Amebiasis: Intestinal amebiasis, extraintestinal amebiasis including cases of liver abscess and symptom less-cyst passers.
  • Giardiasis (lambliasis).
  • Prevention and treatment Of postoperative anaerobic infections.
  • Acute ulcerative gingivitis and acute dental infections.
  • Urogenital trichomoniasis.

DOSAGE

It is recommended to be taken at least 1 hour before meals

Intestinal amebiasis ( for 5 days)

  • From 1 to 3 years: 200 mg every 8 hours.
  • From 3 to 7 years: 200 mg every 6 hours.
  • from 7 to 10 years: 400 mg every’ 8 hours.

Extra-intestinal amebiasis (for 5 to 10 days)

  • From 1 to 3 years: 100-200 mg every 8 hours.
  • From 3 to 7 years: 100-200 mg every 6 hours.
  • From 7 to 10 years: 200-400 mg every 8 hours.

Giardiasis (for 3 days)

  • From 1 to 3 years: 500 mg Once daily.
  • From 3 to 7 years: 600-800 mg once daily.
  • From 7 to 10 years: 1 g once daily.

Anaerobic infections (for 7 days)

7.5 mg/KG every 8 hours.

Acute ulcerative gingivitis (for 3 days)

  • From 1 to 3 years: 50 mg every 8 hours.
  • From 3 to 7 years: 100 mg every 12 hours.
  • From 7 to 10 years: 100 mg every 8 hours.

Urogenital trichomoniasis ( for 7 days)

  • From 1 to 3 years: 50 mg every 8 hours.
  • From 3 to 7 years: 100 mg every 12 hours.
  • From 7 to 10 years: 100 mg every 8 hours.
Metrozole suspension
Metrozole suspension

SIDE EFFECTS

Following Of metronidazole-containing preparations, mild effects such as mild gastrointestinal discomfort. unpleasant metallic and darkening Of the urine may occur.

CONTRAINDICATIONS

Hypersensitivity to benzoyl metronidazole.

DRUG INTERACTIONS

The anticoagulant effect of warfarin is potentiated. Phenobarbitone increases the metabolism of metronidazole. Cimetidine inhibits the metabolism Of metronidazole. Phenytoin metabolism is inhibited.

PRECAUTIONS

Dosage should be adjusted in patients with hepatic dysfunction.

Should be used with caution in patients with active CNS diseases.

PACKING

  • STORAGE: Keep at a temperature (15—30)degree.
  • Keep out of the reach of children.

PRODUCED BY: MEMPHIS PHARMACEUTICALS.

Patient information leaflet

ENG - Patient Information Leaflet
Metrozole – Patient Information Leaflet
Patient_Information_Leaflet
ميتروزول شراب: النشرة الداخلية

Categories: Agents that reduce seizure threshold; Alimentary Tract and Metabolism; Anti-Bacterial Agents; Anti-Infective Agents; Antibacterials for Systemic Use; Antiinfectives and Antiseptics for Local Oral Treatment; Antiinfectives for Systemic Use; Antiparasitic Agents; Antiprotozoals; Cytochrome P-450 CYP2A6 Substrates; Cytochrome P-450; Drugs for Acid Related Disorders; Drugs for Peptic Ulcer and Gastro-Oesophageal Reflux Disease (Gord); Gynecological Anti Infectives and Antiseptics; Imidazole Derivatives; Imidazoles Miscellaneous Antiprotozoals; Miscellaneous Local Anti-infectives; Nitro Compounds; Nitroimidazole Antimicrobial.

Tags: Imidazole derivatives; metronidazole; J01XD01.

Metrozole- Alternatives

English Alternatives
Metrozole Alternatives
  1. AMRIZOLE 125MG/5ML SUSP. 120ML.
  2. DUMOZOL 125MG/5ML SUSP. 125ML.
  3. ENTOPHAR 125MG/5ML SUSP. 120ML.
  4. FLAGYL 125MG/5ML SUSP. 100ML.
  5. METROZOLE 125MG/5ML SUSP. 120 ML.
  6. Flazol 125 suspension.
  7. Anazol 125 suspension.
  8. Negazole Suspension.

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